Fragile X Syndrome Free Essay, Term Paper and Book Report
Fragile X Syndrome
Fragile X syndrome is a sex-linked trait. It is caused by a break or weakness on the long arm of the X chromosome. It can be traced back to a mutation in a gene called the FMR1 gene. With Fragile X, the FMR1 gene is much bigger than normal where the CGG is repeated. The average number of repeats is 30 for a normal person. A carrier of fragile X will usually have 50-200 repeats. A person with fragile X has 200 or more repeats. A person with fragile X has a full mutation. When there are so many repeats in the gene, methyl groups attach to the cytosine and turns the gene off. The gene then can not produce any FMRP (Fragile X Mental Retardation Protein). If a person doesnt have the protein, they can develop mental impairment and other characteristics. Fragile X is estimated to occur in 1 in 1,200 males and 1 in 2,500 females. It occurs in all racial, ethnic, and socioeconomic groups. It is the most common genetic disease and is the most commonly inherited cause of learning disabilities and mental retardation. 10 percent of all cases of mental retardation are......
Word Count: 478
Page Count: 1.9 (250 words a page / double spaced)
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